Detecting bilateral abnormalities with voxel-based morphometry
نویسندگان
چکیده
منابع مشابه
Voxel-Based Morphometry
The human brain is in a state of constant change and adaptation. This may be driven either by normal developmental or aging processes or by the effects of learning, training, and new occurrences in daily life. In addition to these aforementioned changes, more systematic influences such as gender, disease, and genes affect the brain’s structure. Using magnetic resonance imaging, brain changes an...
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An underlying assumption of the above parametric approach is that the process is a = Gaussian field, i.e., its statistical characteristics, including its roughness parameter (or its reciprocal, the smoothness ) ), are the same at each point in the image. The FWHM of the process should be constant in all directions and across all voxels in the image. While these assumptions are reasonable for fu...
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In neuroimaging, voxel based morphometry (VBM) has been a valuable tool of identifying brain-wide differences between populations. One of the key elements of VBM is to define a space for voxelwise comparisons. However, errors in this mapping to common space and variations of brain morphology, both natural and pathologic can result in false positives. In this work we explore a new framework, whe...
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At its simplest, voxel-based morphometry (VBM) involves a voxel-wise comparison of the local concentration of gray matter between two groups of subjects. The procedure is relatively straightforward and involves spatially normalizing high-resolution images from all the subjects in the study into the same stereotactic space. This is followed by segmenting the gray matter from the spatially normal...
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BACKGROUND Structural brain abnormalities associated with delusions in Alzheimer's disease are poorly understood. In addition, whether the neural substrate underlying the delusions develops before the onset of the delusions is unclear. In this study, we used a voxel-based morphometry approach to examine the existence of regional structural abnormalities at baseline in patients with Alzheimer's ...
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ژورنال
عنوان ژورنال: Human Brain Mapping
سال: 2000
ISSN: 1065-9471,1097-0193
DOI: 10.1002/1097-0193(200011)11:3<223::aid-hbm80>3.0.co;2-f